Metabolome + Genome Re-sequencing Correlation Analysis1
Metabolomics, based on high-throughput mass spectrometry, can decompose a small number of macroscopic phenotypes into metabolic molecular phenotypes, and find significantly associated metabolic indicators and gene variants through mGWAS, which can more directly reveal the molecular mechanism behind macroscopic phenotypes such as diseases.
Features and Advantages
Several metabolic phenotypes
More phenotypes allowing discovery of more associated genes
Quantifiable and accurate phenotypes leading to more precise SNP localization
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