Human Microbiome

The human microbiome is an intricate and dynamic ecosystem with profound impacts on human health. Characterizing and understanding the role of the microbiome requires cutting-edge multi-omics tools. Next-generation sequencing (NGS) and mass spectrometry based multi-omics services are transforming human microbiome research. They provide a comprehensive view of the microbial composition and functional capabilities. Our integrated services involving next-generation sequencing (NGS) and mass spectrometry empower researchers to gain valuable insights into microbiome composition, function, host-microbe interactions, and disease associations.
With our support, researchers can leverage the full potential of multi-omics to advance microbiome science. Our expertise and technologies facilitate microbiome profiling, functional analyses, longitudinal tracking, strain identification, and host-microbiome genetic interaction studies. Researchers can gain a comprehensive understanding of the human microbiome and translate findings into precision diagnostics and therapeutics.

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Multi-omics in Human Microbiome

Microbial Profiling: Identify and characterize microbes via DNA sequencing for community composition analysis.

Functional Analysis: RNA sequencing reveals gene expression patterns and metabolic functions.

Host-Microbe Interactions: Genomic and transcriptomic insights into crosstalk, immune modulation and metabolic pathways.

Disease Links: Microbial signatures associated with health conditions via sequencing.

Longitudinal Studies: Track temporal changes in composition and expression over time.

Metagenomics: Analyze collective genetic potential for pathways, resistance and function.

Proteomics and metabolomics: as powerful tools for studying the human microbiome, allowing researchers to identify key proteins and metabolites and understand the complex interactions between host and microbe.

NGS Applications

Metagenomics

Metagenomic sequencing of the human microbiome reveals the collective microbial genome to understand the role of bacterial communities in health and disease.

Mass Spectrometry Applications

Proteomics

Mass spectrometry proteomics services provide detailed characterisation of microbial proteins and their interactions with human hosts, allowing researchers studying the human microbiome to comprehend the functional functions of commensal bacteria, pinpoint pathogenic pathways, and find indicators of dysbiosis.

Metabolomics

Researchers studying the human microbiome can characterize functional pathways in commensal bacteria, discover metabolites linked to dysbiosis, and clarify host-microbe metabolic interactions by characterizing the metabolic products of microbial communities using mass spectrometry metabolomics services.

Multi-omics

Mass spectrometry multi-omics services provide human microbiome researchers with a thorough systems-level view of host-microbe interactions and help them identify new diagnostic and therapeutic targets related to dysbiosis by integrating proteomics, metabolomics, and genomics data from microbial communities and host samples.

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